Promethazine Hydrochloride and Codeine

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Promethazine Hydrochloride and Codeine:

Definition: A combination medication containing promethazine (antihistamine) and codeine (opioid cough suppressant).

Composition:

– Promethazine hydrochloride (12.5-25 mg/5 mL)
– Codeine phosphate (10-30 mg/5 mL)

Uses:

1. Relieves cough and congestion
2. Treats allergies, itching, and hives
3. Manages mild to moderate pain
4. Induces sedation and relaxation

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Effects:

1. Cough suppression
2. Antihistamine effects (drowsiness, dry mouth)
3. Pain relief
4. Sedation

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What is promethazine?

These tablets contain 10mg of promethazine hydrochloride, a type of medicine known as a phenothiazine. Promethazine hydrochloride has a variety of medical uses:

• Treatment of allergic conditions such as hay fever or rashes

• Prevention or treatment of nausea and vomiting (i.e. travel sickness)

• Short-term relief of insomnia (difficulty sleeping) in adults

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What is the recommended dosage?

The recommended dosage for promethazine will depend on your age and what you’re planning to use the tablets for. Always follow your doctor or pharmacist’s specific advice on how to take this medicine for your condition.

For allergies:

Children 5-10 years: a single dose of either one or two tablets (10mg or 20mg) given at night, or one tablet (10mg) given twice a day. Do not give more than two tablets (20mg) in one day.

Adults and children over 10 years old: start with one tablet (10mg) twice a day. This can be increased to a maximum of two tablets (20mg) three times a day.

Prevention of nausea and vomiting due to travel sickness:

Children 5-10 years: a single tablet to be taken the night before the journey. This may be repeated after 6-8 hours if necessary.

Adults and children over 10 years old: two tablets to be taken the night before the journey. This may be repeated after 6-8 hours if necessary.

Insomnia treatment for adults:

Two to five tablets (20mg to 50mg) as a single dose at night time.

How does promethazine hydrochloride work?

Promethazine hydrochloride is a type of medicine called a phenothiazine, which works by blocking a chemical called histamine that your body produces during an allergic reaction. This medicine also works directly on the brain to help you feel more relaxed.

Will these tablets make me feel drowsy?

Promethazine hydrochloride is a drowsy medicine. That means you may feel sleepy after taking this medicine in the evening and the following morning too. If you feel drowsy after taking promethazine, do not drive or operate machinery until this side effect has subsided.

Can I drink alcohol while taking this medicine?

Do not drink any alcoholic drinks while taking promethazine tablets. This is because alcohol can affect the way promethazine works and may worsen some side effects.

Are these tablets suitable for pregnant or breastfeeding women?

If you are pregnant, think you may be pregnant or are trying to become pregnant, speak to a doctor or Chemist4U pharmacist for advice before taking promethazine tablets. You must not take this medicine two weeks before birth or if you are breastfeeding. This is because small amounts of the medicine may pass into your milk and harm your baby.

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When should promethazine not be used?

Promethazine tablets are not suitable for some groups of people. You must avoid this medicine if:

• You are allergic to promethazine hydrochloride or any of the other ingredients

• You are currently, or have recently been taking a medicine for depression called a monoamine oxidase inhibitor (MAOI) in the last 14 days

• The person taking this medicine is under 5 years old

• The person taking this medicine is unconscious or suffers from severe dizziness, drowsiness or headache